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File Extension Details
The FASTA format is a text-based format for representing either nucleotide sequences or amino acid (protein) sequences, in which nucleotides or amino acids are represented using single-letter codes. The format also allows for sequence names and comments to precede the sequences. Originally developed for the FASTA software package, it has since become a near-universal standard in the field of bioinformatics and computational biology. A FASTA file typically begins with a single-line description, followed by lines of sequence data. The description line is distinguished from the sequence data by a greater-than symbol ('>') in the first column. The word immediately following the '>' symbol is the unique identifier of the sequence, while the remainder of the line provides additional metadata. Because FASTA files are stored in plain text, they are easily human-readable and can be manipulated using basic text editors or command-line tools. However, specialized bioinformatics software is generally used to process these files for tasks such as sequence alignment, homology searching, and genome assembly. The format's simplicity and flexibility have ensured its continued relevance despite the emergence of more complex formats like FASTQ, which includes quality scores.
Programs that can open and work with .fasta files
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About .fasta files
To open a .fasta file, you need compatible software. Here are some options:
To convert a .fasta file to another format, you can:
Like any file type, .fasta files can be safe or potentially risky depending on their source:
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